I have been disappointed with the update to the layout. The pages are the right hand side. As a left handed person, I often use a touch screen or key strokes for many things. It wasn't great at the top, but I'm left handed, I'm used to adapting. The right hand navigation is disappointing. :( Please test more with lefties before you change things! Thank you!
Adminisverma (Admin, Adobe) commented
Thanks for your valuable feedback.
We will evaluate and iterate on how Reader can be enhanced to support Left handed users
Meanwhile, we hope that as you get familiar with the new interface, you can be more productive & get more out of Reader.