My Windows 10 Pro installation started crashing regularly by exhausting virtual memory, i.e. commit charge. After eliminating applications one-by-one, I determined that Adobe Acrobat Pro 2020 was the culprit. If I boot the machine and launch open Resource Monitor and watch the Commit Charge meter, all is fine with Commit Charge at or below 10%. The moment I start Adobe Acrobat Pro 2020, the Commit Charge will start to slowly ramp up. After an hour or two, it will run up to 100% and start causing Resource-Exhaustion-Detector errors, and eventually, the machine will hang. If I do these same steps, but instead of letting Commit Charge get fully exhausted, quit Acrobat before it hits 100%, Commit Charge will instantly drop back to the 10-15% level it was before launching Acrobat. I think this pretty conclusively proves Acrobat is the cause of the problem.

This machine has 32 GB of physical RAM. Running Windows 10 Pro version 2004, fully patched to OS Build 19041.867. Acrobat is version 2020.001.30020.